Laboratory of chemistry and biochemistry of anticancer drugs

Research grants since 2006:

PhD grant MniSW No. N405 127340 ‘Metabolism of antitumor triazoloacridinone C-1305 via UDP-glucuronosyltransferases and the influence of these agent on the enzymatic activity of cytochrome P450 enzymes and UDP-glucuronosyltransferases,’ 05.2011 – 05.2013, head of the grant – Dr. Zofia Mazerska.
PhD grant MNiSW No. N401 073536 ‘Metabolism of antitumor triazoloacridinone and 9-amino-1-nitroacridine derivatives in tumor cells and the effect of these agents on the enzymatic activity and gene expression of cytochrome P450 enzymes,’ 2010-2012, head of the grant – Dr. Zofia Mazerska.
Grant MNiSW No. N401 073536 ‘Antitumor imidazoacridinone C-1311 and triazoloacridinone C-1305 as inhibitors of receptor tyrosine kinase FLT3 – potential application in therapy of acute myeloblastic leukemias (AML),’ 2009-2011, head of the grant – Dr. Ewa Augustin.
PhD grant MNiSW No. N405 306036 ‘In vitro studies on the effect of antitumor imidazoacridinone derivative, C-1311, on the activity of selected cytochrome P450 isoenzyme,’ 04. 2009 – 09.2010, head of the grant – Dr. Zofia Mazerska.
PhD grant MNiSW No. N405 046 32/3029 ‘In vitro metabolic transformations of antitumor 9-amino-1-nitroacridine derivative, C-1748, in terms of phase I of clinical trials of this compound,’ 04. 2007 – 04.2009, head of the grant – Dr. Zofia Mazerska.
Grant MNiSW No. N401 159 32/3045 ‘The effect of metabolic transformations of antitumor imidazoacridinone derivative C-1311 on cancer cell death,’ 03. 2007 – 03.2009, head of the grant – Dr. Zofia Mazerska.
Grant Xanthus Life Science Inc., Cambridge, MA, USA ‘Pharmacological biochemistry of imidazoacridinone C-1311,’ 03.2002 – 03.2006, head of the grant – prof. Jerzy Konopa.
PhD grant MNiSW No. 2 P05F06828 ‘Studies on the ability of anticancer drugs and compounds to crosslinking mitochondria DNA in cancer cells,’ 03.2005 – 09.2006, head of the grant – prof. Jerzy Konopa.
PhD grant MNiSW No. 2 P05A 117 28 ‘Studies of the effect of 4-methyl-1-nitroacridine C-1748 and 1-nitroacridine C-857 on cell cycle and induction of apoptosis of cancer cells,’ 04.2005 – 10.2006, head of the grant – prof. Jerzy Konopa.
Grant MNiSW No. 2PO5A5226 ‘In vitro metabolic transformations of antitumor imidazoacridinone derivative, C-1311, in terms of its clinical trials,’04.2004 – 04.2006, head of the grant – Dr. Zofia Mazerska.




	MAIN PAGE GROUP RESEARCH PROFILE SELECTED PAPERS SELECTED CONFERENCE REPORTS GRANTS SCIENTIFIC COOPERATION OFFER PhD STUDIES MSc/BEng STUDIES EDUCATION LABORATORY wersja polska		GRANTS Research grants since 2006: PhD grant MniSW No. N405 127340 ‘Metabolism of antitumor triazoloacridinone C-1305 via UDP-glucuronosyltransferases and the influence of these agent on the enzymatic activity of cytochrome P450 enzymes and UDP-glucuronosyltransferases,’ 05.2011 – 05.2013, head of the grant – Dr. Zofia Mazerska. PhD grant MNiSW No. N401 073536 ‘Metabolism of antitumor triazoloacridinone and 9-amino-1-nitroacridine derivatives in tumor cells and the effect of these agents on the enzymatic activity and gene expression of cytochrome P450 enzymes,’ 2010-2012, head of the grant – Dr. Zofia Mazerska. Grant MNiSW No. N401 073536 ‘Antitumor imidazoacridinone C-1311 and triazoloacridinone C-1305 as inhibitors of receptor tyrosine kinase FLT3 – potential application in therapy of acute myeloblastic leukemias (AML),’ 2009-2011, head of the grant – Dr. Ewa Augustin. PhD grant MNiSW No. N405 306036 ‘In vitro studies on the effect of antitumor imidazoacridinone derivative, C-1311, on the activity of selected cytochrome P450 isoenzyme,’ 04. 2009 – 09.2010, head of the grant – Dr. Zofia Mazerska. PhD grant MNiSW No. N405 046 32/3029 ‘In vitro metabolic transformations of antitumor 9-amino-1-nitroacridine derivative, C-1748, in terms of phase I of clinical trials of this compound,’ 04. 2007 – 04.2009, head of the grant – Dr. Zofia Mazerska. Grant MNiSW No. N401 159 32/3045 ‘The effect of metabolic transformations of antitumor imidazoacridinone derivative C-1311 on cancer cell death,’ 03. 2007 – 03.2009, head of the grant – Dr. Zofia Mazerska. Grant Xanthus Life Science Inc., Cambridge, MA, USA ‘Pharmacological biochemistry of imidazoacridinone C-1311,’ 03.2002 – 03.2006, head of the grant – prof. Jerzy Konopa. PhD grant MNiSW No. 2 P05F06828 ‘Studies on the ability of anticancer drugs and compounds to crosslinking mitochondria DNA in cancer cells,’ 03.2005 – 09.2006, head of the grant – prof. Jerzy Konopa. PhD grant MNiSW No. 2 P05A 117 28 ‘Studies of the effect of 4-methyl-1-nitroacridine C-1748 and 1-nitroacridine C-857 on cell cycle and induction of apoptosis of cancer cells,’ 04.2005 – 10.2006, head of the grant – prof. Jerzy Konopa. Grant MNiSW No. 2PO5A5226 ‘In vitro metabolic transformations of antitumor imidazoacridinone derivative, C-1311, in terms of its clinical trials,’04.2004 – 04.2006, head of the grant – Dr. Zofia Mazerska.